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Mutational escape from CD8(+) T cell immunity: HCV evolution, from chimpanzees to man
The mechanisms by which the hepatitis C virus (HCV) establishes persistence are not yet fully understood. Previous chimpanzee and now human studies suggest that mutations within MHC class I–restricted HCV epitopes might contribute to viral escape from cytotoxic T lymphocyte (CTL) responses. However,...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213256/ https://www.ncbi.nlm.nih.gov/pubmed/15939787 http://dx.doi.org/10.1084/jem.20050808 |