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Mutational escape from CD8(+) T cell immunity: HCV evolution, from chimpanzees to man

The mechanisms by which the hepatitis C virus (HCV) establishes persistence are not yet fully understood. Previous chimpanzee and now human studies suggest that mutations within MHC class I–restricted HCV epitopes might contribute to viral escape from cytotoxic T lymphocyte (CTL) responses. However,...

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Detalles Bibliográficos
Autores principales:	Bowen, David G., Walker, Christopher M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213256/ https://www.ncbi.nlm.nih.gov/pubmed/15939787 http://dx.doi.org/10.1084/jem.20050808

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