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Cellular immune selection with hepatitis C virus persistence in humans
Hepatitis C virus (HCV) infection frequently persists despite substantial virus-specific cellular immune responses. To determine if immunologically driven sequence variation occurs with HCV persistence, we coordinately analyzed sequence evolution and CD8(+) T cell responses to epitopes covering the...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213263/ https://www.ncbi.nlm.nih.gov/pubmed/15939790 http://dx.doi.org/10.1084/jem.20050121 |