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Mimicry of a constitutively active pre–B cell receptor in acute lymphoblastic leukemia cells

Pre–B cells undergo apoptosis unless they are rescued by pre–B cell receptor–dependent survival signals. We previously showed that the BCR-ABL1 kinase that is expressed in pre–B lymphoblastic leukemia bypasses selection for pre–B cell receptor–dependent survival signals. Investigating possible inter...

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Detalles Bibliográficos
Autores principales: Feldhahn, Niklas, Klein, Florian, Mooster, Jana L., Hadweh, Paul, Sprangers, Mieke, Wartenberg, Maria, Bekhite, Mohamed M., Hofmann, Wolf-Karsten, Herzog, Sebastian, Jumaa, Hassan, Rowley, Janet D., Müschen, Markus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213268/
https://www.ncbi.nlm.nih.gov/pubmed/15939795
http://dx.doi.org/10.1084/jem.20042101