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15-epi-lipoxin A(4)–mediated Induction of Nitric Oxide Explains How Aspirin Inhibits Acute Inflammation

The established model for the mechanism of action of aspirin is the inhibition of prostaglandin synthesis. However, this has never fully explained aspirin's repertoire of antiinflammatory properties. We found in acute pleuritis that aspirin, but not salicylate, indomethacin, or piroxicam, incre...

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Detalles Bibliográficos
Autores principales: Paul-Clark, Mark J., van Cao, Thong, Moradi-Bidhendi, Niloufar, Cooper, Dianne, Gilroy, Derek W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213311/
https://www.ncbi.nlm.nih.gov/pubmed/15238606
http://dx.doi.org/10.1084/jem.20040566