Bacterial Inhibition of Phosphatidylcholine Synthesis Triggers Apoptosis in the Brain

Streptococcus pneumoniae is the most common cause of bacterial meningitis of high mortality and morbidity. Neurological sequelae include paralysis, mental retardation, and learning disorders. In humans, neurons of the hippocampus undergo apoptosis as a result of meningitis. Phosphatidylcholine (PtdC...

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Detalles Bibliográficos
Autores principales: Zweigner, Janine, Jackowski, Suzanne, Smith, Shannon H., van der Merwe, Marie, Weber, Joerg R., Tuomanen, Elaine I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213312/
https://www.ncbi.nlm.nih.gov/pubmed/15238609
http://dx.doi.org/10.1084/jem.20032100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213312/
https://www.ncbi.nlm.nih.gov/pubmed/15238609
http://dx.doi.org/10.1084/jem.20032100

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