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Bacterial Inhibition of Phosphatidylcholine Synthesis Triggers Apoptosis in the Brain
Streptococcus pneumoniae is the most common cause of bacterial meningitis of high mortality and morbidity. Neurological sequelae include paralysis, mental retardation, and learning disorders. In humans, neurons of the hippocampus undergo apoptosis as a result of meningitis. Phosphatidylcholine (PtdC...
Autores principales: | Zweigner, Janine, Jackowski, Suzanne, Smith, Shannon H., van der Merwe, Marie, Weber, Joerg R., Tuomanen, Elaine I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213312/ https://www.ncbi.nlm.nih.gov/pubmed/15238609 http://dx.doi.org/10.1084/jem.20032100 |
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