Essential Role of Lung Plasmacytoid Dendritic Cells in Preventing Asthmatic Reactions to Harmless Inhaled Antigen

Tolerance is the usual outcome of inhalation of harmless antigen, yet T helper (Th) type 2 cell sensitization to inhaled allergens induced by dendritic cells (DCs) is common in atopic asthma. Here, we show that both myeloid (m) and plasmacytoid (p) DCs take up inhaled antigen in the lung and present...

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Detalles Bibliográficos
Autores principales: de Heer, Hendrik Jan, Hammad, Hamida, Soullié, Thomas, Hijdra, Daniëlle, Vos, Nanda, Willart, Monique A.M., Hoogsteden, Henk C., Lambrecht, Bart N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213319/
https://www.ncbi.nlm.nih.gov/pubmed/15238608
http://dx.doi.org/10.1084/jem.20040035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213319/
https://www.ncbi.nlm.nih.gov/pubmed/15238608
http://dx.doi.org/10.1084/jem.20040035

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