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Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow

Long-lived plasma cells, residing primarily in the bone marrow, continuously secrete antibody and provide an important component of humoral memory. However, when such cells secrete autoantibodies or become transformed, they can be pathogenic. We have shown recently that the transcriptional repressor...

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Detalles Bibliográficos
Autores principales: Shapiro-Shelef, Miriam, Lin, Kuo-I, Savitsky, David, Liao, Jerry, Calame, Kathryn
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213334/
https://www.ncbi.nlm.nih.gov/pubmed/16314438
http://dx.doi.org/10.1084/jem.20051611