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Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow
Long-lived plasma cells, residing primarily in the bone marrow, continuously secrete antibody and provide an important component of humoral memory. However, when such cells secrete autoantibodies or become transformed, they can be pathogenic. We have shown recently that the transcriptional repressor...
Autores principales: | Shapiro-Shelef, Miriam, Lin, Kuo-I, Savitsky, David, Liao, Jerry, Calame, Kathryn |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213334/ https://www.ncbi.nlm.nih.gov/pubmed/16314438 http://dx.doi.org/10.1084/jem.20051611 |
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