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Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity

Sulfatide derived from the myelin stimulates a distinct population of CD1d-restricted natural killer T (NKT) cells. Cis-tetracosenoyl sulfatide is one of the immunodominant species in myelin as identified by proliferation, cytokine secretion, and CD1d tetramer staining. The crystal structure of mous...

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Detalles Bibliográficos
Autores principales: Zajonc, Dirk M., Maricic, Igor, Wu, Douglass, Halder, Ramesh, Roy, Keshab, Wong, Chi-Huey, Kumar, Vipin, Wilson, Ian A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213337/
https://www.ncbi.nlm.nih.gov/pubmed/16314439
http://dx.doi.org/10.1084/jem.20051625