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Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity
Sulfatide derived from the myelin stimulates a distinct population of CD1d-restricted natural killer T (NKT) cells. Cis-tetracosenoyl sulfatide is one of the immunodominant species in myelin as identified by proliferation, cytokine secretion, and CD1d tetramer staining. The crystal structure of mous...
Autores principales: | Zajonc, Dirk M., Maricic, Igor, Wu, Douglass, Halder, Ramesh, Roy, Keshab, Wong, Chi-Huey, Kumar, Vipin, Wilson, Ian A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213337/ https://www.ncbi.nlm.nih.gov/pubmed/16314439 http://dx.doi.org/10.1084/jem.20051625 |
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