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Autoantibodies make a U-turn: the toll hypothesis for autoantibody specificity

Like the immune response itself, our efforts to understand the “rules” for self–nonself discrimination are constantly evolving. The discovery of pattern recognition receptors—the Toll-like receptor (TLR) family in particular—shifted the emphasis of self–nonself recognition from lymphocytes functioni...

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Detalles Bibliográficos
Autores principales: Martin, David A., Elkon, Keith B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213341/
https://www.ncbi.nlm.nih.gov/pubmed/16330812
http://dx.doi.org/10.1084/jem.20052228