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Autoantibodies make a U-turn: the toll hypothesis for autoantibody specificity
Like the immune response itself, our efforts to understand the “rules” for self–nonself discrimination are constantly evolving. The discovery of pattern recognition receptors—the Toll-like receptor (TLR) family in particular—shifted the emphasis of self–nonself recognition from lymphocytes functioni...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213341/ https://www.ncbi.nlm.nih.gov/pubmed/16330812 http://dx.doi.org/10.1084/jem.20052228 |