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Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells

If irradiated tumor cells could be rendered immunogenic, they would provide a safe, broad, and patient-specific array of antigens for immunotherapies. Prior approaches have emphasized genetic transduction of live tumor cells to express cytokines, costimulators, and surrogate foreign antigens. We ask...

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Detalles Bibliográficos
Autores principales: Liu, Kang, Idoyaga, Juliana, Charalambous, Anna, Fujii, Shin-ichiro, Bonito, Anthony, Mordoh, Jose, Wainstok, Rosa, Bai, Xue-Feng, Liu, Yang, Steinman, Ralph M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213343/
https://www.ncbi.nlm.nih.gov/pubmed/16330814
http://dx.doi.org/10.1084/jem.20050956