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Cysteine Protease Inhibitors Cure an Experimental Trypanosoma cruzi Infection
Trypanosoma cruzi is the causative agent of Chagas' disease. The major protease, cruzain, is a target for the development of new chemotherapy. We report the first successful treatment of an animal model of Chagas' disease with inhibitors designed to inactivate cruzain. Treatment with fluor...
Autores principales: | Engel, Juan C., Doyle, Patricia S., Hsieh, Ivy, McKerrow, James H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213346/ https://www.ncbi.nlm.nih.gov/pubmed/9705954 |
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