Repression of B7.2 on Self-reactive B Cells Is Essential to Prevent Proliferation and Allow Fas-mediated Deletion by CD4(+) T Cells

Peripheral tolerance mechanisms normally prevent delivery of T cell help to anergic self-reactive B cells that accumulate in the T zones of spleen and lymph nodes. Chronic exposure to self-antigens desensitizes B cell antigen receptor (BCR) signaling on anergic B cells so that they are not stimulate...

Descripción completa

Detalles Bibliográficos
Autores principales: Rathmell, Jeffrey C., Fournier, Sylvie, Weintraub, Bennett C., Allison, James P., Goodnow, Christopher C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213352/
https://www.ncbi.nlm.nih.gov/pubmed/9705947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213352/
https://www.ncbi.nlm.nih.gov/pubmed/9705947

Ejemplares similares