Complementation of Lymphotoxin α Knockout Mice with Tumor Necrosis Factor–expressing Transgenes Rectifies Defective Splenic Structure and Function

Lymphotoxin (LT)α knockout mice, as well as double LTα/tumor necrosis factor (TNF) knockout mice, show a severe splenic disorganization with nonsegregating T/B cell zones and complete absence of primary B cell follicles, follicular dendritic cell (FDC) networks, and germinal centers. In contrast, as...

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Detalles Bibliográficos
Autores principales: Alexopoulou, Lena, Pasparakis, Manolis, Kollias, George
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213356/
https://www.ncbi.nlm.nih.gov/pubmed/9705956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213356/
https://www.ncbi.nlm.nih.gov/pubmed/9705956

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