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Antigen-dependent CD28 Signaling Selectively Enhances Survival and Proliferation in Genetically Modified Activated Human Primary T Lymphocytes

Most tumor cells function poorly as antigen-presenting cells in part because they do not express costimulatory molecules. To provide costimulation to T lymphocytes that recognize tumor cells, we constructed a CD28-like receptor specific for G(D2), a ganglioside overexpressed on the surface of neurob...

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Detalles Bibliográficos
Autores principales: Krause, Anja, Guo, Hong-Fen, Latouche, Jean-Baptiste, Tan, Cuiwen, Cheung, Nai-Kong  V., Sadelain, Michel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213361/
https://www.ncbi.nlm.nih.gov/pubmed/9705944