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Antigen-dependent CD28 Signaling Selectively Enhances Survival and Proliferation in Genetically Modified Activated Human Primary T Lymphocytes
Most tumor cells function poorly as antigen-presenting cells in part because they do not express costimulatory molecules. To provide costimulation to T lymphocytes that recognize tumor cells, we constructed a CD28-like receptor specific for G(D2), a ganglioside overexpressed on the surface of neurob...
Autores principales: | Krause, Anja, Guo, Hong-Fen, Latouche, Jean-Baptiste, Tan, Cuiwen, Cheung, Nai-Kong V., Sadelain, Michel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213361/ https://www.ncbi.nlm.nih.gov/pubmed/9705944 |
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