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Multidrug Resistance Protein 1 Protects the Oropharyngeal Mucosal Layer and the Testicular Tubules against Drug-induced Damage

The multidrug resistance protein 1 (MRP1) gene encodes a transporter protein that helps to protect cells against xenobiotics. Elevated levels of MRP1 in tumor cells can result in active extrusion of a wide range of (anticancer) drugs with different cellular targets, a phenomenon called multidrug res...

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Detalles Bibliográficos
Autores principales: Wijnholds, Jan, Scheffer, George L., van der  Valk, Martin, van der  Valk, Paul, Beijnen, Jos H., Scheper, Rik J., Borst, Piet
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213389/
https://www.ncbi.nlm.nih.gov/pubmed/9730882