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Multidrug Resistance Protein 1 Protects the Oropharyngeal Mucosal Layer and the Testicular Tubules against Drug-induced Damage
The multidrug resistance protein 1 (MRP1) gene encodes a transporter protein that helps to protect cells against xenobiotics. Elevated levels of MRP1 in tumor cells can result in active extrusion of a wide range of (anticancer) drugs with different cellular targets, a phenomenon called multidrug res...
Autores principales: | Wijnholds, Jan, Scheffer, George L., van der Valk, Martin, van der Valk, Paul, Beijnen, Jos H., Scheper, Rik J., Borst, Piet |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213389/ https://www.ncbi.nlm.nih.gov/pubmed/9730882 |
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