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Differential Regulation and ATP Requirement for Caspase-8 and Caspase-3 Activation during CD95- and Anticancer Drug–induced Apoptosis

Apoptosis is induced by different stimuli, among them triggering of the death receptor CD95, staurosporine, and chemotherapeutic drugs. In all cases, apoptosis is mediated by caspases, although it is unclear how these diverse apoptotic stimuli cause protease activation. Two regulatory pathways have...

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Detalles Bibliográficos
Autores principales: Ferrari, Davide, Stepczynska, Ania, Los, Marek, Wesselborg, Sebastian, Schulze-Osthoff, Klaus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213396/
https://www.ncbi.nlm.nih.gov/pubmed/9730899