Efficient Peripheral Clonal Elimination of B Lymphocytes in MRL/lpr Mice Bearing Autoantibody Transgenes

Peripheral B cell tolerance was studied in mice of the autoimmune-prone, Fas-deficient MRL/ lpr.H-2(d) genetic background by introducing a transgene that directs expression of membrane-bound H-2K(b) antigen to liver and kidney (MT-K(b)) and a second transgene encoding antibody reactive with this ant...

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Detalles Bibliográficos
Autores principales: Kench, Jennifer A., Russell, David M., Nemazee, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213400/
https://www.ncbi.nlm.nih.gov/pubmed/9730892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213400/
https://www.ncbi.nlm.nih.gov/pubmed/9730892

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