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Selective Expression and Functions of Interleukin 18 Receptor on T Helper (Th) Type 1 but not Th2 Cells

Interleukin (IL)-18 induces interferon (IFN)-γ synthesis and synergizes with IL-12 in T helper type 1 (Th1) but not Th2 cell development. We report here that IL-18 receptor (IL-18R) is selectively expressed on murine Th1 but not Th2 cells. IL-18R mRNA was expressed constitutively and consistently in...

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Detalles Bibliográficos
Autores principales: Xu, Damo, Chan, Woon Ling, Leung, Bernard P., Hunter, David, Schulz, Kerstin, Carter, Robert W., McInnes, Iain B., Robinson, John H., Liew, Foo Y.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213413/
https://www.ncbi.nlm.nih.gov/pubmed/9782125