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Dendritic Cells Induce Autoimmune Diabetes and Maintain Disease via De Novo Formation of Local Lymphoid Tissue

Activation of autoreactive T cells can lead to autoimmune diseases such as insulin-dependent diabetes mellitus (IDDM). The initiation and maintenance of IDDM by dendritic cells (DC), the most potent professional antigen-presenting cells, were investigated in transgenic mice expressing the lymphocyti...

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Detalles Bibliográficos
Autores principales: Ludewig, Burkhard, Odermatt, Bernhard, Landmann, Salome, Hengartner, Hans, Zinkernagel, Rolf M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213416/
https://www.ncbi.nlm.nih.gov/pubmed/9782126