Pancreatic β Cell–specific Expression of  Thioredoxin, an Antioxidative and Antiapoptotic Protein, Prevents Autoimmune and Streptozotocin-induced Diabetes

The cytotoxicity of reactive oxygen intermediates (ROIs) has been implicated in the destruction of pancreatic β cells in insulin-dependent diabetes mellitus (IDDM). Thioredoxin (TRX), a redox (reduction/oxidation)-active protein, has recently been shown to protect cells from oxidative stress and apo...

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Detalles Bibliográficos
Autores principales: Hotta, Mizuo, Tashiro, Fumi, Ikegami, Hiroshi, Niwa, Hitoshi, Ogihara, Toshio, Yodoi, Junji, Miyazaki, Jun-ichi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213419/
https://www.ncbi.nlm.nih.gov/pubmed/9782121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213419/
https://www.ncbi.nlm.nih.gov/pubmed/9782121

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