Somatic Mutation of the Cd95 Gene in Human B Cells as a Side-Effect of the Germinal Center Reaction

Somatic hypermutation specifically modifies rearranged immunoglobulin (Ig) genes in germinal center (GC) B cells. However, the bcl-6 gene can also acquire somatic mutations during the GC reaction, indicating that certain non-Ig genes can be targeted by the somatic hypermutation machinery. The CD95 g...

Descripción completa

Detalles Bibliográficos
Autores principales: Müschen, Markus, Re, Daniel, Jungnickel, Berit, Diehl, Volker, Rajewsky, Klaus, Küppers, Ralf
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213498/
https://www.ncbi.nlm.nih.gov/pubmed/11120779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213498/
https://www.ncbi.nlm.nih.gov/pubmed/11120779

Ejemplares similares