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Hla-Dm Recognizes the Flexible Conformation of Major Histocompatibility Complex Class II

DM facilitates formation of high affinity complexes of peptide–major histocompatibility complex (MHC) by release of class II MHC–associated invariant chain peptide (CLIP). This has been proposed to occur through discrimination of complex stability. By probing kinetic and conformational intermediates...

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Detalles Bibliográficos
Autores principales: Chou, Chih-Ling, Sadegh-Nasseri, Scheherazade
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213500/
https://www.ncbi.nlm.nih.gov/pubmed/11120767