Protective Immunity to Bordetella pertussis Requires Both B Cells and Cd4(+) T Cells for Key Functions Other than Specific Antibody Production

To investigate the fundamental nature of protective immunity to Bordetella pertussis, we studied intranasal immunization of adult mice with formalin-fixed B. pertussis (FFBP), followed by aerosol B. pertussis challenge. Mice given two doses of FFBP intranasally completely cleared a subsequent pertus...

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Detalles Bibliográficos
Autores principales: Leef, Mary, Elkins, Karen L., Barbic, Jerko, Shahin, Roberta D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213518/
https://www.ncbi.nlm.nih.gov/pubmed/10839801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213518/
https://www.ncbi.nlm.nih.gov/pubmed/10839801

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