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Fcα Receptor (Cd89) Mediates the Development of Immunoglobulin a (Iga) Nephropathy (Berger's Disease): Evidence for Pathogenic Soluble Receptor–Iga Complexes in Patients and Cd89 Transgenic Mice

The pathogenesis of immunoglobulin A (IgA) nephropathy (IgAN), the most prevalent form of glomerulonephritis worldwide, involves circulating macromolecular IgA1 complexes. However, the molecular mechanism(s) of the disease remain poorly understood. We report here the presence of circulating soluble...

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Detalles Bibliográficos
Autores principales: Launay, Pierre, Grossetête, Béatrice, Arcos-Fajardo, Michelle, Gaudin, Emmanuelle, Torres, Sonia P., Beaudoin, Lucie, Patey-Mariaud de Serre, Natacha, Lehuen, Agnès, Monteiro, Renato C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213528/
https://www.ncbi.nlm.nih.gov/pubmed/10839814