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Viral Escape by Selection of Cytotoxic T Cell–Resistant Variants in Influenza a Virus Pneumonia

Antigenic variation is a strategy exploited by influenza viruses to promote survival in the face of the host adaptive immune response and constitutes a major obstacle to efficient vaccine development. Thus, variation in the surface glycoproteins hemagglutinin and neuraminidase is reflected by change...

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Detalles Bibliográficos
Autores principales: Price, Graeme E., Ou, Rong, Jiang, Hong, Huang, Lei, Moskophidis, Demetrius
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213532/
https://www.ncbi.nlm.nih.gov/pubmed/10839802