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Signaling via β(2) Integrins Triggers Neutrophil-Dependent Alteration in Endothelial Barrier Function

Activation of polymorphonuclear leukocytes (PMNs) and adhesion to the endothelial lining is a major cause of edema formation. Although known to be dependent on the function of β(2) integrins (CD11/CD18), the precise mechanisms by which adherent PMNs may impair endothelial barrier capacity remain unc...

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Detalles Bibliográficos
Autores principales: Gautam, Narinder, Herwald, Heiko, Hedqvist, Per, Lindbom, Lennart
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213534/
https://www.ncbi.nlm.nih.gov/pubmed/10839800