Intrinsic Electrostatic Potential in the BK Channel Pore: Role in Determining Single Channel Conductance and Block

The internal vestibule of large-conductance Ca(2+) voltage-activated K(+) (BK) channels contains a ring of eight negative charges not present in K(+) channels of lower conductance (Glu386 and Glu389 in hSlo) that modulates channel conductance through an electrostatic mechanism (Brelidze, T.I., X. Ni...

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Detalles Bibliográficos
Autores principales: Carvacho, Ingrid, Gonzalez, Wendy, Torres, Yolima P., Brauchi, Sebastian, Alvarez, Osvaldo, Gonzalez-Nilo, Fernando D., Latorre, Ramon
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213566/
https://www.ncbi.nlm.nih.gov/pubmed/18227273
http://dx.doi.org/10.1085/jgp.200709862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213566/
https://www.ncbi.nlm.nih.gov/pubmed/18227273
http://dx.doi.org/10.1085/jgp.200709862

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