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Agonist-dependent Single Channel Current and Gating in α(4)β(2)δ and α(1)β(2)γ(2S) GABA(A) Receptors

The family of γ-aminobutyric acid type A receptors (GABA(A)Rs) mediates two types of inhibition in the mammalian brain. Phasic inhibition is mediated by synaptic GABA(A)Rs that are mainly comprised of α(1), β(2), and γ(2) subunits, whereas tonic inhibition is mediated by extrasynaptic GABA(A)Rs comp...

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Detalles Bibliográficos
Autores principales: Keramidas, Angelo, Harrison, Neil L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213567/
https://www.ncbi.nlm.nih.gov/pubmed/18227274
http://dx.doi.org/10.1085/jgp.200709871