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Locus-specific and activity-independent gene repositioning during early tumorigenesis

The mammalian genome is highly organized within the cell nucleus. The nuclear position of many genes and genomic regions changes during physiological processes such as proliferation, differentiation, and disease. It is unclear whether disease-associated positioning changes occur specifically or are...

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Detalles Bibliográficos
Autores principales: Meaburn, Karen J., Misteli, Tom
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213600/
https://www.ncbi.nlm.nih.gov/pubmed/18195100
http://dx.doi.org/10.1083/jcb.200708204