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Locus-specific and activity-independent gene repositioning during early tumorigenesis
The mammalian genome is highly organized within the cell nucleus. The nuclear position of many genes and genomic regions changes during physiological processes such as proliferation, differentiation, and disease. It is unclear whether disease-associated positioning changes occur specifically or are...
Autores principales: | Meaburn, Karen J., Misteli, Tom |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213600/ https://www.ncbi.nlm.nih.gov/pubmed/18195100 http://dx.doi.org/10.1083/jcb.200708204 |
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