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A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence
The peripheral nuclear lamina, which is largely but not entirely associated with inactive chromatin, is considered to be an important determinant of nuclear structure and gene expression. We present here an inducible system to target a genetic locus to the nuclear lamina in living mammalian cells. U...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213611/ https://www.ncbi.nlm.nih.gov/pubmed/18195101 http://dx.doi.org/10.1083/jcb.200706060 |