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The microtubule-based motor Kar3 and plus end–binding protein Bim1 provide structural support for the anaphase spindle

In budding yeast, the mitotic spindle is comprised of 32 kinetochore microtubules (kMTs) and ∼8 interpolar MTs (ipMTs). Upon anaphase onset, kMTs shorten to the pole, whereas ipMTs increase in length. Overlapping MTs are responsible for the maintenance of spindle integrity during anaphase. To dissec...

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Detalles Bibliográficos
Autores principales: Gardner, Melissa K., Haase, Julian, Mythreye, Karthikeyan, Molk, Jeffrey N., Anderson, MaryBeth, Joglekar, Ajit P., O'Toole, Eileen T., Winey, Mark, Salmon, E.D., Odde, David J., Bloom, Kerry
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213616/
https://www.ncbi.nlm.nih.gov/pubmed/18180364
http://dx.doi.org/10.1083/jcb.200710164