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The microtubule-based motor Kar3 and plus end–binding protein Bim1 provide structural support for the anaphase spindle
In budding yeast, the mitotic spindle is comprised of 32 kinetochore microtubules (kMTs) and ∼8 interpolar MTs (ipMTs). Upon anaphase onset, kMTs shorten to the pole, whereas ipMTs increase in length. Overlapping MTs are responsible for the maintenance of spindle integrity during anaphase. To dissec...
Autores principales: | Gardner, Melissa K., Haase, Julian, Mythreye, Karthikeyan, Molk, Jeffrey N., Anderson, MaryBeth, Joglekar, Ajit P., O'Toole, Eileen T., Winey, Mark, Salmon, E.D., Odde, David J., Bloom, Kerry |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213616/ https://www.ncbi.nlm.nih.gov/pubmed/18180364 http://dx.doi.org/10.1083/jcb.200710164 |
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