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Dynein-mediated apical localization of crumbs transcripts is required for Crumbs activity in epithelial polarity
Asymmetrical localization of transcripts coupled with localized translation constitutes an important mechanism widely deployed to regulate gene activity in a spatial manner. The conserved transmembrane protein Crumbs (Crb) is an important regulator of epithelial polarity. However, it remains unclear...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213619/ https://www.ncbi.nlm.nih.gov/pubmed/18195099 http://dx.doi.org/10.1083/jcb.200707007 |