Cargando…

Dynein-mediated apical localization of crumbs transcripts is required for Crumbs activity in epithelial polarity

Asymmetrical localization of transcripts coupled with localized translation constitutes an important mechanism widely deployed to regulate gene activity in a spatial manner. The conserved transmembrane protein Crumbs (Crb) is an important regulator of epithelial polarity. However, it remains unclear...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zhouhua, Wang, Liwei, Hays, Thomas S., Cai, Yu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213619/
https://www.ncbi.nlm.nih.gov/pubmed/18195099
http://dx.doi.org/10.1083/jcb.200707007