Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis

The RNA-binding protein HuR affects cell fate by regulating the stability and/or the translation of messenger RNAs that encode cell stress response proteins. In this study, we delineate a novel regulatory mechanism by which HuR contributes to stress-induced cell death. Upon lethal stress, HuR transl...

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Detalles Bibliográficos
Autores principales: Mazroui, Rachid, Di Marco, Sergio, Clair, Eveline, von Roretz, Christopher, Tenenbaum, Scott A., Keene, Jack D., Saleh, Maya, Gallouzi, Imed-Eddine
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213623/
https://www.ncbi.nlm.nih.gov/pubmed/18180367
http://dx.doi.org/10.1083/jcb.200709030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213623/
https://www.ncbi.nlm.nih.gov/pubmed/18180367
http://dx.doi.org/10.1083/jcb.200709030

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