Isolation of anti-toxin single domain antibodies from a semi-synthetic spiny dogfish shark display library

BACKGROUND: Shark heavy chain antibody, also called new antigen receptor (NAR), consists of one single Variable domain (V(H)), containing only two complementarity-determining regions (CDRs). The antigen binding affinity and specificity are mainly determined by these two CDRs. The good solubility, ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jinny L, Anderson, George P, Goldman, Ellen R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213646/
https://www.ncbi.nlm.nih.gov/pubmed/18021450
http://dx.doi.org/10.1186/1472-6750-7-78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213646/
https://www.ncbi.nlm.nih.gov/pubmed/18021450
http://dx.doi.org/10.1186/1472-6750-7-78

Ejemplares similares