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Isolation of anti-toxin single domain antibodies from a semi-synthetic spiny dogfish shark display library

BACKGROUND: Shark heavy chain antibody, also called new antigen receptor (NAR), consists of one single Variable domain (V(H)), containing only two complementarity-determining regions (CDRs). The antigen binding affinity and specificity are mainly determined by these two CDRs. The good solubility, ex...

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Detalles Bibliográficos
Autores principales:	Liu, Jinny L, Anderson, George P, Goldman, Ellen R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213646/ https://www.ncbi.nlm.nih.gov/pubmed/18021450 http://dx.doi.org/10.1186/1472-6750-7-78

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