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Sample matching by inferred agonal stress in gene expression analyses of the brain

BACKGROUND: Gene expression patterns in the brain are strongly influenced by the severity and duration of physiological stress at the time of death. This agonal effect, if not well controlled, can lead to spurious findings and diminished statistical power in case-control comparisons. While some rece...

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Detalles Bibliográficos
Autores principales: Li, Jun Z, Meng, Fan, Tsavaler, Larisa, Evans, Simon J, Choudary, Prabhakara V, Tomita, Hiroaki, Vawter, Marquis P, Walsh, David, Shokoohi, Vida, Chung, Tisha, Bunney, William E, Jones, Edward G, Akil, Huda, Watson, Stanley J, Myers, Richard M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213675/
https://www.ncbi.nlm.nih.gov/pubmed/17892578
http://dx.doi.org/10.1186/1471-2164-8-336