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Altering coenzyme specificity of Pichia stipitis xylose reductase by the semi-rational approach CASTing
BACKGROUND: The NAD(P)H-dependent Pichia stipitis xylose reductase (PsXR) is one of the key enzymes for xylose fermentation, and has been cloned into the commonly used ethanol-producing yeast Saccharomyces cerevisiae. In order to eliminate the redox imbalance resulting from the preference of this en...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213684/ https://www.ncbi.nlm.nih.gov/pubmed/18028553 http://dx.doi.org/10.1186/1475-2859-6-36 |