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Altering coenzyme specificity of Pichia stipitis xylose reductase by the semi-rational approach CASTing

BACKGROUND: The NAD(P)H-dependent Pichia stipitis xylose reductase (PsXR) is one of the key enzymes for xylose fermentation, and has been cloned into the commonly used ethanol-producing yeast Saccharomyces cerevisiae. In order to eliminate the redox imbalance resulting from the preference of this en...

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Detalles Bibliográficos
Autores principales: Liang, Ling, Zhang, Jingqing, Lin, Zhanglin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213684/
https://www.ncbi.nlm.nih.gov/pubmed/18028553
http://dx.doi.org/10.1186/1475-2859-6-36