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Large-Scale Population Study of Human Cell Lines Indicates that Dosage Compensation Is Virtually Complete

X chromosome inactivation in female mammals results in dosage compensation of X-linked gene products between the sexes. In humans there is evidence that a substantial proportion of genes escape from silencing. We have carried out a large-scale analysis of gene expression in lymphoblastoid cell lines...

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Detalles Bibliográficos
Autores principales: Johnston, Colette M, Lovell, Frances L, Leongamornlert, Daniel A, Stranger, Barbara E, Dermitzakis, Emmanouil T, Ross, Mark T
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213701/
https://www.ncbi.nlm.nih.gov/pubmed/18208332
http://dx.doi.org/10.1371/journal.pgen.0040009