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Large-Scale Population Study of Human Cell Lines Indicates that Dosage Compensation Is Virtually Complete
X chromosome inactivation in female mammals results in dosage compensation of X-linked gene products between the sexes. In humans there is evidence that a substantial proportion of genes escape from silencing. We have carried out a large-scale analysis of gene expression in lymphoblastoid cell lines...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213701/ https://www.ncbi.nlm.nih.gov/pubmed/18208332 http://dx.doi.org/10.1371/journal.pgen.0040009 |