Cargando…
Large-Scale Population Study of Human Cell Lines Indicates that Dosage Compensation Is Virtually Complete
X chromosome inactivation in female mammals results in dosage compensation of X-linked gene products between the sexes. In humans there is evidence that a substantial proportion of genes escape from silencing. We have carried out a large-scale analysis of gene expression in lymphoblastoid cell lines...
Autores principales: | Johnston, Colette M, Lovell, Frances L, Leongamornlert, Daniel A, Stranger, Barbara E, Dermitzakis, Emmanouil T, Ross, Mark T |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213701/ https://www.ncbi.nlm.nih.gov/pubmed/18208332 http://dx.doi.org/10.1371/journal.pgen.0040009 |
Ejemplares similares
-
Rapid Evolution of Complete Dosage Compensation in Poecilia
por: Metzger, David C H, et al.
Publicado: (2021) -
The genetics of regulatory variation in the human genome
por: Stranger, Barbara E, et al.
Publicado: (2005) -
From DNA to RNA to disease and back: The 'central dogma' of regulatory disease variation
por: Stranger, Barbara E, et al.
Publicado: (2006) -
Decoding dosage compensation
por: Deng, Xinxian, et al.
Publicado: (2007) -
Complete Dosage Compensation and Sex-Biased Gene Expression in the Moth Manduca sexta
por: Smith, Gilbert, et al.
Publicado: (2014)