Positive Selection and Increased Antiviral Activity Associated with the PARP-Containing Isoform of Human Zinc-Finger Antiviral Protein

Intrinsic immunity relies on specific recognition of viral epitopes to mount a cell-autonomous defense against viral infections. Viral recognition determinants in intrinsic immunity genes are expected to evolve rapidly as host genes adapt to changing viruses, resulting in a signature of adaptive evo...

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Detalles Bibliográficos
Autores principales: Kerns, Julie A, Emerman, Michael, Malik, Harmit S
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213710/
https://www.ncbi.nlm.nih.gov/pubmed/18225958
http://dx.doi.org/10.1371/journal.pgen.0040021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213710/
https://www.ncbi.nlm.nih.gov/pubmed/18225958
http://dx.doi.org/10.1371/journal.pgen.0040021

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