A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene Loci

CpG islands (CGIs) are dense clusters of CpG sequences that punctuate the CpG-deficient human genome and associate with many gene promoters. As CGIs also differ from bulk chromosomal DNA by their frequent lack of cytosine methylation, we devised a CGI enrichment method based on nonmethylated CpG aff...

Descripción completa

Detalles Bibliográficos
Autores principales: Illingworth, Robert, Kerr, Alastair, DeSousa, Dina, Jørgensen, Helle, Ellis, Peter, Stalker, Jim, Jackson, David, Clee, Chris, Plumb, Robert, Rogers, Jane, Humphray, Sean, Cox, Tony, Langford, Cordelia, Bird, Adrian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2214817/
https://www.ncbi.nlm.nih.gov/pubmed/18232738
http://dx.doi.org/10.1371/journal.pbio.0060022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2214817/
https://www.ncbi.nlm.nih.gov/pubmed/18232738
http://dx.doi.org/10.1371/journal.pbio.0060022

Ejemplares similares